Article
A novel eukaryotic RdRP-dependent small RNA pathway represses antiviral immunity by controlling an ERK pathway component in the black-legged tick
2021-09-20
Abstract excerpt
Small regulatory RNAs (sRNAs) are involved in antiviral defense and gene regulation. Although roles of RNA-dependent RNA Polymerases (RdRPs) in sRNA biology are extensively studied in nematodes, plants and fungi, understanding of RdRP homologs in other animals is still lacking. Here, we study sRNAs in the ISE6 cell line, which is derived from the black-legged tick, an important vector of human and animal pathogens...
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Identifiers and source
- Literature Corpus work
- 98dc00d2-ee9f-5868-9bcf-a332e5d5f7cc
- DOI
- 10.1101/2021.09.19.460923