Article

The Novel Hub Genes of Klinefelter Syndrome Affect Sperm Cell Differentiation: Analysis Based on RNA-Seq and scRNA-Seq Data

2022-01-24

Abstract excerpt

<h4>Objective: </h4> In this study, the Hub genes that are closely associated with spermatogenesis in klinefelter syndrome (KS) patients were identified, mainly through transcriptomic and single-cell RNA sequencing (scRNA-seq)data. Methods Transcriptome data were obtained from 3 adult 4 fetal KS patients and 8 normal individuals. ScRNA-seq data were obtained from 1 adult KS patient and 4 normal individuals. The d...

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Literature Corpus work: 16ea16b5-dbfd-5f16-9a09-8f7c74ffc7aa
DOI: 10.21203/rs.3.rs-1198365/v1

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