Article

Structural basis of biofilm formation mediated by the <i>Pseudomonas aeruginosa</i> fibrillar adhesin CdrA

2026-07-13

Abstract excerpt

Many bacteria, including the important human pathogen Pseudomonas aeruginosa , are naturally found in antibiotic-tolerant, multicellular biofilms. Cell-cell interactions within P. aeruginosa biofilms are mediated by a large fibrillar adhesin called CdrA in an extracellular polysaccharide-dependent manner. Here, we report an electron cryomicroscopy structure of the 60 kDa CdrA adhesive N-terminus, which combined...

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Literature Corpus work: 98571cd6-e445-570f-bc16-2f4565ebef86
DOI: 10.64898/2026.07.13.738186

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