Article
The Versatile Pseudomonas aeruginosa Biofilm Matrix Protein CdrA Promotes Aggregation through Different Extracellular Exopolysaccharide Interactions.
Journal of bacteriology - 8 Sept 2020
Reichhardt Courtney, Jacobs Holly M, Matwichuk Michael, Wong Cynthis, Wozniak Daniel J, Parsek Matthew R
Abstract excerpt
Pseudomonas aeruginosa is an important pathogen that causes chronic infections that involve multicellular aggregates called biofilms. Within biofilms, bacteria are surrounded in a protective extracellular matrix of proteins, exopolysaccharides (EPS), and DNA. A key P. aeruginosa matrix protein is an extracellular adhesin called CdrA, which promotes aggregation by binding to the EPS Psl and via CdrA-CdrA...
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