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Leukemogenesis in Acute Lymphoblastic Leukemia through the Lens of Developmental Dynamics of Lymphoid Progenitor Cells: a systematic review

2024-07-14

Abstract excerpt

<h4>Objective</h4> The objective of this study is to investigate how lymphoid progenitor mechanisms contribute to the leukemogenesis in Acute Lymphoblastic Leukemia. <h4>Background</h4> Acute Lymphoblastic Leukemia (ALL), the leading childhood cancer, remains challenging despite treatment advances. ALL originates from aberrant clonal expansion of immature lymphoid progenitor cells (LPCs) due to genetic abnormaliti...

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Literature Corpus work
98473f91-bb25-53c0-8e62-bb43f3271567
DOI
10.1101/2024.07.14.24310322
Open publication

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