Article
Identification of a peroxidase inhibitor that enhances kanamycin activity
2020-10-13
Abstract excerpt
<h4>Background</h4> The threat of antimicrobial resistance calls for more efforts in basic science, drug discovery, and clinical development, particularly gram-negative carbapenem-resistant pathogens. <h4>Objectives and methods</h4> Whole-cell–based screening was performed to identify novel antibacterial agents against Acinetobacter baumannii ATCC19606. Spontaneously resistant mutant selection, whole-genome seq...
Topics
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- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- Berberine and alkaloids research
- Microbial metabolism and enzyme function
- Mycobacterium research and diagnosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Tuberculosis Research and Epidemiology
Identifiers and source
- Literature Corpus work
- 975d5626-6d37-5cab-9c93-6bcf41884df1
- DOI
- 10.1101/2020.10.12.336933
