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Directed growth during somatic cell fusion in <i>Neurospora crassa</i> requires contributions from two distinct MAP kinase pathways

2020-08-13

Abstract excerpt

Somatic cell fusion in Neurospora crassa depends on two MAP kinases, MAK-1 and MAK-2, but their precise contributions to directed growth have remained unclear. Using analog-sensitive alleles and live-cell imaging, we found that MAK-1 activity is required for RAC-1 activation and polarized actin assembly, while MAK-2 controls the positioning of RAC-1 and actin at the fusion tips. Inhibition of MAK-1 disrupted cell...

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Literature Corpus work
970a3b28-af23-5b4b-a5cf-02a99156bbf3
DOI
10.1101/2020.08.12.246843
Open publication

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Directed growth during somatic cell fusion in <i>Neurospora crassa</i> requires contributions from two distinct MAP kinase pathwaysDOI 10.1101/2020.08.12.246843
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