Article
Identification and characterization of genes required for cell-to-cell fusion in Neurospora crassa.
Eukaryotic cell - 1 Aug 2011
Fu Ci, Iyer Priyadarshini, Herkal Amrita, Abdullah Julia, Stout Angela, Free Stephen J
Abstract excerpt
A screening procedure was used to identify cell fusion (hyphal anastomosis) mutants in the Neurospora crassa single gene deletion library. Mutants with alterations in 24 cell fusion genes required for cell fusion between conidial anastomosis tubes (CATs) were identified and characterized. The cell fusion genes identified included 14 genes that are likely to function in signal transduction pathways needed for cell...
Topics
- Cell Fusion
- Fungal Proteins
- Gene Knockout Techniques
- Genetic Association Studies
- Hyphae
- Intracellular Signaling Peptides and Proteins
- Membrane Proteins
- Neurospora crassa
- Phenotype
- Spores, Fungal
- Transcription Factors
- Transport Vesicles