Spatial Cell Type Enrichment Predicts Mouse Brain Connectivity

Abstract excerpt

<title>Abstract</title> <p>A fundamental question in neuroscience is whether and how the brain’s molecular, cellular and cytoarchitectonic properties govern its inter-regional structural connectivity. Several recent studies have leveraged spatial transcriptomic data to infer the mouse mesoscale connectome with high accuracy, indicating that there is a strong biological link between whole-brain gene expression and...

Topics

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• High-Throughput Nucleotide Sequencing
• Hypothalamus
• Mesencephalon
• Neuropeptides
• Neurotransmitter Agents
• Rhombencephalon
• Single-Cell Gene Expression Analysis
• Transcriptome

Identifiers and source

Literature Corpus work

97004ec2-3e75-552b-88f4-fcbe9231b6fc

DOI

10.21203/rs.3.rs-1479454/v1