Article

Genomic inversion drives small colony variant formation and increased virulence in <i>P. aeruginosa</i>

2018-07-09

Abstract excerpt

Phenotypic change is a hallmark of bacterial adaptation during chronic infection. In the case of chronic Pseudomonas aeruginosa lung infection in patients with cystic fibrosis, well-characterised phenotypic variants include mucoid and small colony variants (SCVs). It has previously been shown that SCVs can be reproducibly isolated from the murine lung following the establishment of chronic infection with mucoid...

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Literature Corpus work: 96fb6704-6902-53ae-bca7-adece4e95fbe
DOI: 10.1101/356386

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