Article

Insertion sequences drive the emergence of a highly adapted human pathogen

2018-10-25

Abstract excerpt

Taxonomic outliers of Pseudomonas aeruginosa of environmental origin have recently emerged as infectious for humans. Here we present the first genome-wide analysis of an isolate that caused fatal hemorrhagic pneumonia. We demonstrate that, in two sequential clones, CLJ1 and CLJ3, recovered from a patient with chronic pulmonary disease, insertion of a mobile genetic element into the P. aeruginosa chromosome affec...

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Identifiers and source

Literature Corpus work: 2d96fb45-1a88-503b-b58d-aad3ec473f23
DOI: 10.1101/452334

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