Article

In vivo imaging of reactive oxygen species after myocardial ischemia-reperfusion injury: a large animal multimodal imaging and transcriptomic study

2025-12-08

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Reactive oxygen species (ROS) contribute to myocardial ischemia-reperfusion injury (IRI), but in-vivo data on the spatial myocardial distribution and systemic effects of ROS after IRI remain limited. This multimodal CMR and PET/CT study aimed to non-invasively image ROS activity in a clinically-relevant swine model of IRI using [18F]ROStrace, a fluorine-18-labeled analogue o...

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Literature Corpus work: 96b7670d-3dbc-5983-990b-bc967ed813c6
DOI: 10.64898/2025.12.04.691257

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