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Article

Evaluation of time-dependent phenotypes of myocardial ischemia-reperfusion in mice.

Aging - 10 Oct 2023

Meng Xiang-Min, Yuan Jing-Han, Zhou Zhen-Fang, Feng Qi-Pu, Zhu Bing-Mei

Abstract excerpt

BACKGROUND: A mouse model of myocardial ischemia-reperfusion (I/R) is widely used to study myocardial ischemia-reperfusion injury (I/RI). However, few studies focus on the direct comparison of the extent of pathological events resulting from variant durations of ischemia and reperfusion process. METHODS: A mouse model of I/RI was established by ligation and perfusion of the left anterior descending coronary...

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Identifiers

PMID: 37819785
DOI: 10.18632/aging.205103
PMCID: PMC10599719

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