Article

Vascular endothelial growth factor (VEGF) expression and neuroinflammation is increased in the frontopolar cortex of individuals with autism spectrum disorder

2019-05-03

Abstract excerpt

Autism spectrum disorder (ASD) etiology is a complex mixture of genetic and environmental factors, the relative contributions of which varies across patients. Despite complex etiology, researchers observe consistent neurodevelopmental features in ASD patients, notably atypical forebrain cortical development. Growth factors, cytokines, and chemokines are important mediators of forebrain cortical development, but ha...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 96929125-c380-5daf-914d-d2bfcc1aa09f
DOI: 10.1101/627083

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Vascular endothelial growth factor (VEGF) expression and neuroinflammation is increased in the frontopolar cortex of individuals with autism spectrum disorderDOI 10.1101/627083Read

Neuron-specific transcriptomic signatures indicate neuroinflammation and altered neuronal activity in ASD temporal cortexSemantic proximity Read

Expression profiling of autism candidate genes during human brain development implicates central immune signaling pathways.Semantic proximity Read

Transcriptomic analysis in autism spectrum disorder suggests three molecular subtypes with distinct phenotypic profiles and functional pathways.Semantic proximity Read

Brain Transcriptome of Autism Spectrum Disorders and Tourette Syndrome Defines Common Targetable Inflammatory Pathways Involving Cytokines, Complement, and Kinase SignallingSemantic proximity Read

Differential gene expression reveals neurodegeneration pathways in children with autism spectrum disorderSemantic proximity Read

Common targetable inflammatory pathways in brain transcriptome of autism spectrum disorders and Tourette syndromeSemantic proximity Read

Unraveling the immunogenetic landscape of autism spectrum disorder: a comprehensive bioinformatics approach.Semantic proximity Read

Immunogenetics of autism spectrum disorder: A systematic literature review.Semantic proximity Read

Identification of aberrant innate and adaptive immunity based on changes in global gene expression in the blood of adults with autism spectrum disorderSemantic proximity Read

Molecular Profiling of the Hippocampus of Children with Autism Spectrum DisorderSemantic proximity Read

Identification of Important Genes of childhood autism and Construction of the Diagnostic ModelSemantic proximity Read

Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD.Semantic proximity Read