Article

Dynamic dysregulation of IL-6 and genes functional in NETosis, complement and coagulation in severe COVID-19 illness

2020-10-14

Abstract excerpt

Comprehensive and unbiased re-analysis of published blood transcriptome data from patients of COVID-19 reveals significant up-regulation of the gene set functional in NETosis, but no evidence of general “cytokine storm”. In severe COVID-19 illness, there is significant up-regulation of complement and coagulation pathway, and negative correlation between NETosis and respiratory function (oxygen saturation). Interes...

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Identifiers and source

Literature Corpus work: 96741011-8413-5868-a633-36f7a7a3ff7d
DOI: 10.1101/2020.10.13.20211425

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