Article

Bringing Down Cancer Aircraft: Searching For Essential Hypomutated Proteins In Skin Melanoma

2015-06-04

Abstract excerpt

Abstract <h4>Background</h4> We propose an approach to detection of essential proteins required for cancer cell survival. Gene is considered essential if mutation with high functional impact upon function of encoded protein causes death of cancer cell. We draw an analogy between essential cancer proteins and well-known Abraham Wald’s work on estimating the plane critical areas using data on survivability of aircr...

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Literature Corpus work: 966fadeb-dbf8-56e8-8ab9-63cda5e0894b
DOI: 10.1101/020396

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