Article

DNMT1 facilitates proliferation and metastasis of breast cancer by inducing MEG3 promoter methylation in MEG3/miR-494-3p/OTUD4 regulatory axis

2020-12-10

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>To explore the mechanism by which DNMT1 potentiates proliferation and metastasis of breast cancer by inducing MEG3 promoter methylation in MEG3/miR-494-3p/OTUD4 regulatory axis.<bold>Methods:</bold> Human breast cancer cell lines (MCF-7, MDA-MB-231, SKBR3) and human breast epithelial cell line MCF10A were selected for the experiments. The expression levels of DN...

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Literature Corpus work: 96380416-0d7a-58e4-9a59-d8bb3a2c33de
DOI: 10.21203/rs.3.rs-27423/v2

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