Article

Mouse hepatitis virus nsp14 exoribonuclease activity is required for resistance to innate immunity

2017-08-29

Abstract excerpt

<h4> ABSTRACT </h4> Coronaviruses (CoV) are positive-sense RNA viruses that infect numerous mammalian and avian species and are capable of causing severe and lethal disease in humans. CoVs encode several innate immune antagonists that interact with the host innate immune response to facilitate efficient viral replication. CoV non-structural protein 14 (nsp14) encodes 3'-to-5' exoribonuclease activity (ExoN), whi...

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Literature Corpus work: 963029d9-41f6-5d1a-816e-540e53f40dc8
DOI: 10.1101/182196

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