Article

Postnatal inflammation in <i>Apoe</i> <sup>−/−</sup> mice is associated with immune training and atherosclerosis

2021-04-14

Abstract excerpt

<h4>Background and aims</h4> Preterm birth is associated with increased risk of cardiovascular disease (CVD). This may reflect a legacy of inflammatory exposures such as chorioamnionitis, that complicate pregnancies delivering preterm, or recurrent early-life infections, common in preterm infants. We previously reported that experimental chorioamnionitis followed by postnatal inflammation has additive and deleter...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 962a71b4-9f77-573d-a8b9-f209542a37bb
DOI: 10.1101/2021.04.14.439403

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Postnatal inflammation in <i>Apoe</i> <sup>−/−</sup> mice is associated with immune training and atherosclerosisDOI 10.1101/2021.04.14.439403Read

Postnatal inflammation in ApoE-/- mice is associated with immune training and atherosclerosis.Semantic proximity Read

Interleukin-1β induces trained innate immunity in human hematopoietic progenitor cells in vitroSemantic proximity Read

Developmental programming of tissue-resident macrophagesSemantic proximity Read

Maternal Inflammation in Late Gestation Alters Vaccine-Induced Immune Responses in Adult Murine OffspringSemantic proximity Read

Maternal hypercholesterolemia exacerbates atherosclerosis lesions in female offspring through potentiating macrophage polarization toward an inflammatory M1 phenotype.Semantic proximity Read

Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesitySemantic proximity Read

Prenatal Maternal Stress Causes Preterm Birth and Affects Neonatal Adaptive Immunity in MiceSemantic proximity Read

Mouse maternal systemic inflammation at the zygote stage causes blunted cytokine responsiveness in lipopolysaccharide-challenged adult offspringSemantic proximity Read

Transgenerational impact of aberrant inflammation in rat pregnancySemantic proximity Read

LPS versus Poly I:C model: comparison of long-term effects of bacterial and viral maternal immune activation on the offspringSemantic proximity Read

Transcriptional profiling of lung macrophages identifies a predictive signature for inflammatory lung disease in preterm infantsSemantic proximity Read

The Mononuclear Phagocyte System of the Rat.Semantic proximity Read