Article

Mesenteric adipose tissue-derived Klebsiella variicola disrupts intestinal barrier and promotes colitis by type VI secretion system

2022-04-29

Abstract excerpt

<h4>Background: </h4> Mesenteric adipose tissue (MAT) in Crohn’s disease (CD) is associated with transmural inflammation. Extended mesenteric excision can reduce surgical recurrence and improve long-term outcomes. These findings indicate that MAT plays an important role in the pathogenesis of CD. Bacterial translocation has been reported to occur in CD-MAT, but the mechanisms by which translocated bacteria lead to...

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Literature Corpus work: 96240e77-e9ad-5fb7-a4a1-8649df4b61fa
DOI: 10.21203/rs.3.rs-1591924/v1

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