Article

A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland

2010-10-01

Abstract excerpt

Molecular dissection of the signaling pathways that underlie complex biological responses in the mammary epithelium is limited by the difficulty of propagating large numbers of mouse mammary epithelial cells, and by the inability of ribonucleic acid interference-based knockdown approaches to fully ablate gene function. Here we describe a method for the generation of conditionally immortalized mammary epithelial ce...

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Identifiers and source

Literature Corpus work: 960ac27f-e349-5e2a-af22-867e22415e6d
DOI: 10.1186/bcr2728

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