Article

Generative machine learning unlocks the first proteome-wide image of human cells

2026-04-02

Abstract excerpt

The spatial organization of proteins within cells governs virtually all cellular functions. Yet, current imaging technologies can simultaneously visualize only tens of proteins, orders of magnitude below the thousands that populate a single human cell. Here, we present ProtiCelli , a deep generative model that simulates microscopy images for 12,800 human proteins from just three cellular landmark stains. Trained...

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Literature Corpus work: 95ed3a37-d2bb-58b0-b64a-382650e2c0a5
DOI: 10.64898/2026.03.31.715748

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