Article

CLN7 protein functions at the interface between endolysosomes and stress granules to promote cell survival

2025-05-16

Abstract excerpt

<title>Abstract</title> <p>Inherited biallelic mutations in the CLN7 gene result in the variant late infantile onset neuronal ceroid lipofuscinosis, a subtype of Batten disease (BD), a severe and fatal childhood neurodegenerative disease. Intriguingly, CLN7 genetic variants have also been associated with retinopathies, amyotrophic lateral sclerosis, and frontotemporal dementia. CLN7 encodes a transmembrane protei...

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Literature Corpus work: 95cf2a5b-1916-50d2-896b-3d63dca1e066
DOI: 10.21203/rs.3.rs-6520859/v1

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