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Targeted genome sequencing for tuberculosis drug susceptibility testing in South Africa: A proposed diagnostic pipeline

2024-02-02

Abstract excerpt

In July 2023, the World Health Organization (WHO) began recommending targeted next-generation sequencing (tNGS), due to its ability to detect resistance to many drugs with a single test. In March 2023, South Africa further adopted the GeneXpert® XDR cartridge, which detects mutations associated with resistance to second-line injectable drugs. Here, we consider the feasibility for implementing tNGS in South Africa,...

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Literature Corpus work
95cc52f8-c851-5152-aa7f-d987d1b2684d
DOI
10.1099/acmi.0.000740.v2
Open publication

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Targeted genome sequencing for tuberculosis drug susceptibility testing in South Africa: A proposed diagnostic pipelineDOI 10.1099/acmi.0.000740.v2
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