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Article

Optimizing drug-resistant tuberculosis diagnosis: cost-effectiveness of rapid molecular and phenotypic assays in South Africa.

BMC medicine - 9 Feb 2026

Fekadu Ginenus, Tolossa Tadesse, Gao Lan, Tola Habteyes Hailu, Feyissa Tesfaye Regassa, Yang Lianping, Chen Shanquan, Chaiyakunapruk Nathorn, Asfaw Elias, Siegel Martin, Ming Wai Kit

Abstract excerpt

BACKGROUND: Timely detection of drug-resistant tuberculosis (DR-TB) is essential for effective treatment and preventing poor outcomes. Rapid molecular diagnostics are promising alternatives to conventional phenotypic drug susceptibility testing (pDST), offering faster and more accessible detection of resistance. This study evaluated the cost-effectiveness of rapid molecular assays, alone or combined with pDST,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41664022
DOI: 10.1186/s12916-026-04693-3
PMCID: PMC12983700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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