Back to search

Article

C2C12 muscle myotubes, but not kidney proximal tubule HK-2 cells, elevate erythritol synthesis in response to oxidative stress

2023-07-19

Abstract excerpt

<h4>Background</h4> As a biomarker, elevated serum erythritol predicts type 2 diabetes and cardiovascular disease onset. Erythritol was recently shown to be a product of human glucose metabolism through the pentose phosphate pathway. The regulation of erythritol synthesis from glucose has been explored in cancer cells, but not in non-transformed cells. <h4>Objective</h4> The kidneys and skeletal muscle have incr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
95cbec5c-1144-52b0-aa26-492911fdf751
DOI
10.1101/2023.07.18.549518
Open publication

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Click a neighbor to travelStep 1 · 8 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
C2C12 muscle myotubes, but not kidney proximal tubule HK-2 cells, elevate erythritol synthesis in response to oxidative stressDOI 10.1101/2023.07.18.549518
Erythritol synthesis in human cells is elevated in response to oxidative stress and regulated by the non-oxidative pentose phosphate pathwaySemantic proximity
Effects of culture media glucose concentration on LHCN-M2 skeletal muscle cell viability, differentiation and metabolic phenotype: a proof-of-concept study.Semantic proximity
Serum-free cultures of C2C12 cells show different muscle phenotypes which can be estimated by metabolic profiling.Semantic proximity
Protective effect of recombinant human erythropoietin in type II Gaucher disease patient cells by scavenging endoplasmic reticulum stress.Semantic proximity
Sugar transport regulation: comparative characterization of the effect of NADH CoQ reductase deficiency in two cell culture systems.Semantic proximity
A post-mitotic <i>in vitro</i> murine as a model of muscle damage and repairSemantic proximity
Diabetes in a Dish: Modeling and Phenotyping Acute and Chronic Type 2 Diabetes Mellitus In Vitro in Rodent Heart and Skeletal Muscle CellsSemantic proximity
Engineering of human myotubes toward a mature metabolic and contractile phenotypeSemantic proximity
Select a neighboring publication to make it the new centre.