BrainImageR: Spatiotemporal gene set analysis referencing the human brain

Abstract excerpt

<h4>RATIONALE</h4> Neurological molecular analyses such as transcriptomics, epigenetics, and genome-wide association studies must be assessed in the context of the human brain in order to generate biologically meaningful inferences. It is often difficult to access primary human brain tissue; therefore, approximations are made using in vitro modeling or by identifying disease-associated genes from DNA extracted f...

Topics

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• Transcriptome
• Brain
• Gene Expression Profiling
• Genetic Predisposition to Disease
• Genome-Wide Association Study
• Major Depressive Disorder
• Neuroimaging
• Phenotype

Identifiers and source

Literature Corpus work

9551576e-ac2a-5ca8-9d17-73e2edb93cb1

DOI

10.1101/229302