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Article

Novel mutations of PRSS1 gene in patients with pancreatic cancer among Han population.

Chinese medical journal - 5 Jul 2011

Zeng Kai, Liu Qi-cai, Lin Jian-hua, Lin Xin-hua, Zhuang Ze-hao, Gao Feng, Ou Qi-shui

Abstract excerpt

BACKGROUND: A high mortality rate of pancreatic cancer becomes a bottleneck for further treatment with long-term efficacy. It is urgent to find a new mean to predict the early onset of pancreatic cancer accurately. The authors hypothesized that genetic variants of cationic trypsinogen (PRSS1) gene could affect trypsin expression/function and result in abnormal activation of protease activated receptor-2 (PAR-2),...

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Identifiers

PMID: 22088471

Genes

PRSS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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