Article
An Evaluation of Factors Associated With Pathogenic PRSS1, SPINK1, CTFR, and/or CTRC Genetic Variants in Patients With Idiopathic Pancreatitis.
The American journal of gastroenterology - 1 Aug 2017
Jalaly Niloofar Y, Moran Robert A, Fargahi Farshid, Khashab Mouen A, Kamal Ayesha, Lennon Anne Marie, Walsh Christi, Makary Martin A, Whitcomb David C, Yadav Dhiraj, Cebotaru Liudmila, Singh Vikesh K
Abstract excerpt
OBJECTIVES: We evaluated factors associated with pathogenic genetic variants in patients with idiopathic pancreatitis. METHODS: Genetic testing (PRSS1, CFTR, SPINK1, and CTRC) was performed in all eligible patients with idiopathic pancreatitis between 2010 to 2015. Patients were classified into the following groups based on a review of medical records: (1) acute recurrent idiopathic pancreatitis (ARIP) with or...
Topics
- Adult
- Aged
- Carrier Proteins
- Chymotrypsin
- Female
- Genetic Predisposition to Disease
- Genetic Variation
- Humans
- Male
- Middle Aged