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Human Bone Marrow-Derived, Pooled, Allogeneic Mesenchymal Stromal Cells Manufactured From Multiple Donors at Different Times Show Comparable Biological Functions in Vitro, and in Vivo to Repair Limb Ischemia

2021-01-18

Abstract excerpt

<h4>Background: </h4> We have previously demonstrated that a pooled population of BM-derived, allogeneic mesenchymal stromal cells (BMMSC), Stempeucel®-1, produced under good manufacturing practices (GMP) conditions, showed clinical efficacy and safety in patients suffering from critical limb ischemia (CLI) due to Buerger's disease. While Stempeucel®-1 is currently used for CLI and other clinical indications, we w...

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Literature Corpus work
94ab8f97-39b9-51a7-a229-7eb35a0ed985
DOI
10.21203/rs.3.rs-146863/v1
Open publication

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Human Bone Marrow-Derived, Pooled, Allogeneic Mesenchymal Stromal Cells Manufactured From Multiple Donors at Different Times Show Comparable Biological Functions in Vitro, and in Vivo to Repair Limb IschemiaDOI 10.21203/rs.3.rs-146863/v1
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