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Article

In vivo therapeutic potential of mesenchymal stromal cells depends on the source and the isolation procedure.

Stem cell reports - 10 Mar 2015

Bortolotti Francesca, Ukovich Laura, Razban Vahid, Martinelli Valentina, Ruozi Giulia, Pelos Barbara, Dore Franca, Giacca Mauro, Zacchigna Serena

Abstract excerpt

Over the last several years, mesenchymal stromal cells (MSCs) have been isolated from different tissues following a variety of different procedures. Here, we comparatively assess the ex vivo and in vivo properties of MSCs isolated from either adipose tissue or bone marrow by different purification protocols. After MSC transplantation into a mouse model of hindlimb ischemia, clinical and histological analysis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25660405
DOI: 10.1016/j.stemcr.2015.01.001
PMCID: PMC4375942

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MSC

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