Article

scDIG: An R Shiny Application for Interactive Density-Based Gating of Single-Cell Proteomic and Transcriptomic Data

2026-05-22

Abstract excerpt

Delineating biologically meaningful cell populations within single-cell embedding spaces requires methods that balance expert guidance with reproducibility. We present scDIG , a Shiny-based tool that integrates bimodal index-driven feature selection, feature-weighted kernel density estimation, and interactive contour-based gating to define cell populations directly within two-dimensional projections of scRNA-seq...

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Literature Corpus work: 94a626b4-6b87-55d5-b331-9f04a58a7387
DOI: 10.64898/2026.05.20.726609

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