Back to search

Article

COSMIC-based mutation database enhances identification efficiency of HLA-I immunopeptidome

2023-09-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Neoantigens have emerged as a promising area of focus in tumor immunotherapy, with several established strategies aiming to enhance their identification. Human leukocyte antigen class I molecules (HLA-I), which present intracellular immunopeptides to T cells, provide an ideal source for identifying neoantigens. However, solely relying on a mutation database gene...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
943d1268-7111-5a51-a949-9de88e87ca21
DOI
10.21203/rs.3.rs-3346799/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
COSMIC-based mutation database enhances identification efficiency of HLA-I immunopeptidomeDOI 10.21203/rs.3.rs-3346799/v1
COSMIC-based mutation database enhances identification efficiency of HLA-I immunopeptidome.Semantic proximity
INAEME: Integral Neoantigen Analysis with Entirety of Mutational EventsSemantic proximity
INAEME: Integral Neoantigen Analysis with Entirety of Mutational EventsSemantic proximity
Advances and challenges in neoantigen prediction for cancer immunotherapySemantic proximity
The Role of Neoantigens in Cancer ImmunotherapySemantic proximity
Best practices for bioinformatic characterization of neoantigens for clinical utility.Semantic proximity
Main Strategies for the Identification of NeoantigensSemantic proximity
Strategies for neoantigen screening and immunogenicity validation in cancer immunotherapy (Review)Semantic proximity
Application of mass spectrometry-based MHC immunopeptidome profiling in neoantigen identification for tumor immunotherapySemantic proximity
From prediction to precision: how immunopeptidomics advances neoantigen discovery.Semantic proximity
TSNAdb: A Database for Tumor-Specific Neoantigens from Immunogenomics Data AnalysisSemantic proximity
Proteogenomic analysis unveils the HLA Class I presented immunopeptidome in melanoma and EGFR mutant lung adenocarcinomaSemantic proximity
Select a neighboring publication to make it the new centre.