Back to search

Article

Engineering PEG10 assembled endogenous virus-like particles with genetically encoded neoantigen peptides for cancer vaccination

2024-04-27

Abstract excerpt

Tumor neoantigen peptide vaccines hold potential for boosting cancer immunotherapy, yet efficiently co-delivering peptides and adjuvants to antigen-presenting cells in vivo remains challenging. Virus-like particle (VLP), which is a kind of multiprotein structure organized as virus, can deliver therapeutic substances into cells and stimulate immune response. However, the weak targeted delivery of VLP in vivo and it...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
93dab789-4541-5c1a-9be5-d613c56cf037
DOI
10.1101/2024.04.25.591213
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Engineering PEG10 assembled endogenous virus-like particles with genetically encoded neoantigen peptides for cancer vaccinationDOI 10.1101/2024.04.25.591213
Efficient Nanovaccine Delivery in Cancer ImmunotherapySemantic proximity
Carrier-Free Nanovaccine: An Innovative Strategy for Ultrahigh Melanoma Neoantigen LoadingSemantic proximity
Equipping Cancer Cell Membrane Vesicles with Functional DNA as a Targeted Vaccine for Cancer ImmunotherapySemantic proximity
Developments in virus-like particle-based vaccines for infectious diseases and cancerSemantic proximity
Bedside formulation of a personalized multi-neoantigen vaccine against mammary carcinomaSemantic proximity
Genetically Engineered Cytomembrane Nanovaccines for Cancer ImmunotherapySemantic proximity
Recent Progress on the Versatility of Virus-Like ParticlesSemantic proximity
A Peptide-Based Neoantigen Vaccine for Patients With Advanced Pancreatic Cancer Refractory to Standard TreatmentSemantic proximity
Oncolytic adenovirus delivery of neoantigens sensitizes low-mutation tumors to anti-PD-1 therapy and prevents metastasis.Semantic proximity
VLP-mediated delivery of structure-selected neoantigens demonstrates immunogenicity and antitumoral activity in miceSemantic proximity
Neoantigen enriched biomimetic nanovaccine for personalized cancer immunotherapySemantic proximity
Strategies for developing and optimizing cancer vaccinesSemantic proximity
Select a neighboring publication to make it the new centre.