Case Report: Integrating Histomorphology and Multi-marker Immunohistochemical Profiling in the Diagnosis of Classic Dermatofibroma: A Clinical Case Report

Abstract excerpt

<h4>Introduction: </h4> Dermatofibroma (DF), or benign fibrous histiocytoma, is a ubiquitous cutaneous neoplasm. Despite its prevalence, its extensive morphological diversity can create diagnostic gray zones, necessitating a rigorous distinction from aggressive mesenchymal malignancies, most notably dermatofibrosarcoma protuberans (DFSP). Case Presentation A 36-year-old female presented with a slowly enlarging, fi...

Topics

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• Biomarkers, Tumor
• Cardiac tumors and thrombi
• Gene Fusion
• Genetic Predisposition to Disease
• Immunohistochemistry
• Oncogene Proteins, Fusion
• Sarcoma Diagnosis and Treatment
• Skin Neoplasms

Identifiers and source

Literature Corpus work

93b28ac1-ff75-5522-bf42-f7aa285f85b1

DOI

10.12688/f1000research.182738.1