Article
Angiomatoid fibrous histiocytoma occurring at distal/acral extremity sites: clinicopathological and molecular study of 26 cases highlighting frequent myxoid histology and site-dependent genotypic variation.
Virchows Archiv : an international journal of pathology - 1 Sept 2025
Agaimy Abbas, Molligan Jeremy, Alruwaii Fatimah I, Antonescu Cristina R, Demicco Elizabeth G, Dickson Brendan C, Gross John, Michal Michael, Perry Kyle, Tögel Lars, Stoehr Robert, Din Nasir Ud, Folpe Andrew L
Abstract excerpt
Angiomatoid fibrous histiocytoma (AFH) is a rare mesenchymal neoplasm of borderline malignancy (locally recurring, rarely metastasizing), most often involving the limbs, trunk, and head/neck. Rarely, AFH may involve unusual locations. Herein, we characterize the clinicopathologic features of 26 AFH of the distal extremities, including acral sites. The tumors occurred in 19 females and 7 males ranging in age from...
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