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Article

Extranodal Histiocytic Sarcoma: A Clinicopathologic Study of Two Cases and Literature Review.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Jan 2026

Li Jiayu, Liao Qiong

Abstract excerpt

Histiocytic sarcoma (HS) is an extremely rare hematopoietic neoplasm derived from the monocytic/histiocytic/dendritic cell lineage. While sporadic cases of primary soft-tissue HS have been reported, its clinicopathological and molecular features remain incompletely characterized. This study investigates the clinicopathological features of two cases of soft-tissue HS and reviews the relevant literature....

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Source

Identifiers

PMID: 41058101
DOI: 10.1097/PAI.0000000000001287

Genes

BRAF
CD163
CD4
CD68
CDKN2A
CIITA
CREBBP
INPP4B
KMT2D
MSH2
PTEN
RB1
TP53

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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