Article

Dynamic changes in homologous recombination status before and after chemotherapy in advanced ovarian, fallopian tube, and primary peritoneal cancers

2025-11-13

Abstract excerpt

<title>Abstract</title> <p>Objective Homologous recombination (HR) status plays a pivotal role in the management of advanced ovarian, fallopian tube, and primary peritoneal cancers (collectively referred to as ovarian cancers), influencing treatment selection and response to PARP inhibitors. For patients undergoing neoadjuvant chemotherapy (NAC) followed by interval debulking surgery (IDS), clinicians have two op...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 93a10ebb-9343-5e35-8ba6-0bb178874ab9
DOI: 10.21203/rs.3.rs-7947639/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dynamic changes in homologous recombination status before and after chemotherapy in advanced ovarian, fallopian tube, and primary peritoneal cancersDOI 10.21203/rs.3.rs-7947639/v1Read

Dynamic changes in homologous recombination status before and after chemotherapy in advanced ovarian, fallopian tube, and primary peritoneal cancers.Semantic proximity Read

Homologous Recombination Deficiency in Ovarian and Breast Cancers: Biomarkers, Diagnosis, and TreatmentSemantic proximity Read

Homologous recombination deficiency in newly diagnosed FIGO stage III/IV high-grade epithelial ovarian cancer: a multi-national observational study.Semantic proximity Read

Systematic Analysis of Homologous Recombination Deficiency Testing in Ovarian Cancer-Development of Recommendations for Optimal Assay Performance.Semantic proximity Read

[Analysis of homologous recombination deficiency testing in ovarian cancer based on next-generation sequencing].Semantic proximity Read

The clinical pathological characteristics and prognostic Relevance of Homologous Recombination Repair Gene Mutations in Ovarian Cancer Patients：A Retrospective Cohort StudySemantic proximity Read

Germline and somatic mutations in homologous recombination genes predict platinum response and survival in ovarian, fallopian tube, and peritoneal carcinomas.Semantic proximity Read

Implementing HRD Testing in Routine Clinical Practice on Patients with Primary High-Grade Advanced Ovarian CancerSemantic proximity Read

Effectiveness of PARP Inhibitor Maintenance Therapy in Ovarian Cancer by BRCA1/2 and a Scar-Based HRD Signature in Real-World Practice.Semantic proximity Read

Homologous Recombination Deficiency in Ovarian and Breast Cancers: Biomarkers, Diagnosis and TreatmentSemantic proximity Read

Prevalence of Homologous Recombination–Related Gene Mutations Across Multiple Cancer TypesSemantic proximity Read

Prevalence of homologous recombination deficiency in ovarian, primary peritoneal, and/or fallopian tube cancer: results from HALO-Taiwan subset.Semantic proximity Read