Article

The killing capacity analysis of tumor infiltrating cytotoxic lymphocytes and impact on lymph node metastasis in differentiated papillary carcinoma of thyroid with BRAF V600E mutation

2023-09-12

Abstract excerpt

<h4>Background: </h4> Cytotoxic lymphocytes(CLs) express potent toxins,including the perforin(P) and granzyme-B(G),which brings about target cell death.The purpose of this study was to evaluate the killing capacity of tumor infiltrating CLs by means of perforin and granzyme-B analysis,and explore the association with lymph node metastasis in papillary carcinoma of thyroid (PTC) without Hashimoto's Thyroiditis(HT)....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 93735c8f-c1cb-5ad0-8837-0637d9e10445
DOI: 10.21203/rs.3.rs-3328614/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The killing capacity analysis of tumor infiltrating cytotoxic lymphocytes and impact on lymph node metastasis in differentiated papillary carcinoma of thyroid with BRAF V600E mutationDOI 10.21203/rs.3.rs-3328614/v1Read

Killing capacity analysis of tumor-infiltrating cytotoxic lymphocytes and impact on lymph node metastasis in differentiated papillary carcinoma of thyroid with the BRAF V600E mutation.Semantic proximity Read

T cell exhaustion is associated with the risk of papillary thyroid carcinoma and can be a predictive and sensitive biomarker for diagnosis.Semantic proximity Read

Diagnostic and prognostic value of tumor-infiltrating B cells in lymph node metastases of papillary thyroid carcinoma.Semantic proximity Read

Integrating BRAFV600E mutation, ultrasonic and clinicopathologic characteristics for predicting the risk of cervical central lymph node metastasis in papillary thyroid carcinoma.Semantic proximity Read

Integrating US-guided FNAB, BRAFV600E mutation, and clinicopathologic characteristics to predict cervical central lymph-node metastasis in preoperative patients with cN0 papillary thyroid carcinoma.Semantic proximity Read

[Cytotoxic T lymphocytes in peripheral blood and regional lymph nodes in laryngeal cancer patients].Semantic proximity Read

Conventional papillary thyroid carcinoma with intraglandular lymphatic dissemination shows more aggressive features.Semantic proximity Read

Association between diffuse lymphocytic infiltration and papillary thyroid cancer aggressiveness according to the presence of thyroid peroxidase antibody and BRAFV600E mutation.Semantic proximity Read

Phenotypic and functional characterization of lymphocytes in autoimmune thyroiditis and in papillary carcinoma.Semantic proximity Read

[Association between BRAF V600E mutation and central lymph node metastasis in patients with papillary thyroid carcinoma].Semantic proximity Read

Fas/Fas ligand gene polymorphism in patients with papillary thyroid cancer in the Turkish population.Semantic proximity Read

IL-12 immunotherapy of Braf(V600E)-induced papillary thyroid cancer in a mouse model.Semantic proximity Read