Article
Killing capacity analysis of tumor-infiltrating cytotoxic lymphocytes and impact on lymph node metastasis in differentiated papillary carcinoma of thyroid with the BRAF V600E mutation.
Diagnostic pathology - 10 Feb 2024
Liu Xiaogang, Liu Honggang, Wang Lu, Han Yubing, Kong Linghong, Zhang Xinpeng
Abstract excerpt
BACKGROUND: Cytotoxic lymphocytes (CLs) express potent toxins, including perforin (P) and granzyme-B (G), which brings about target cell death. The purpose of this study was to evaluate the killing capacity of tumor-infiltrating CLs by means of P and G analysis, and explore the association with lymph node metastasis in papillary carcinoma of thyroid (PTC) without Hashimoto's thyroiditis (HT). METHODS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.