Article

Sox4 Regulates the Sensitivity of Canine Mammary Gland Tumor Cells to Cisplatin via the Wnt/β-catenin Signaling Pathway

2021-09-02

Abstract excerpt

<h4>Background: </h4> The development of cisplatin resistance is one of the major causes of breast cancer treatment failure, and is associated with changes in Sox4 gene expression. In this study, a cisplatin-resistant cell line, CHMp CIS , was constructed from the cell line CHMp, which was isolated from the primary lesion of a malignant canine mammary gland tumor (CMGT). Sox4 expression was evaluated to assess its...

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Literature Corpus work: 930bfd7b-8773-5bfa-80dc-9ca67f27fc6f
DOI: 10.21203/rs.3.rs-847008/v1

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