Article

Harmonic representations of regions and interactions in spatial transcriptomics

2024-08-19

Abstract excerpt

Spatial transcriptomics technologies enable unbiased measurement of the cell-cell interactions underlying tissue structure and function. However, most unsupervised methods instead focus on identifying tissue regions, representing them as positively covarying low-frequency spatial patterns of gene expression over the tissue. Here, we extend this frequency-based (i.e. harmonic) approach to show that negatively covar...

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Identifiers and source

Literature Corpus work: 9309b3b8-b389-55dd-9cf5-9a03e2624393
DOI: 10.1101/2024.08.14.607982

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