Cisplatin, the Timeless Molecule

Abstract excerpt

Cisplatin was the first metal-based anticancer drug introduced into clinical use. It is a “small” molecule, but it represented a very “big” discovery. Since it was introduced on the market, it has not been withdrawn, despite being not free of side effects, owing to its peculiarity of being highly effective in the treatment of cancer. Anticancer activity of the platinum-based complexes was discovered with this mole...

Topics

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• Chemotherapy-induced organ toxicity mitigation
• Drug Transport and Resistance Mechanisms
• Metal complexes synthesis and properties

Identifiers and source

Literature Corpus work

9294b698-85fc-5606-a4be-ffbbda5689a6

DOI

10.3390/inorganics13070246