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Article

Cisplatin and platinum analogues

1 Dec 1992

Abstract excerpt

Cisplatin is a critically important antineoplastic agent employed in treating patients who have a broad spectrum of neoplasms. Resistance to this agent poses a serious clinical dilemma. The objective of this review is to summarize the principal mechanisms that contribute to cytotoxicity by this agent and underlie resistance. Knowledge of these processes provides a rational basis for developing therapeutic...

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Identifiers

PMID: 1457521
DOI: 10.1097/00001622-199212000-00012

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Source receipt: pubmed, retrieved 7 Sept 2026.

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