Article

Distinct neural substrates of affective distress and communicative disability in head and neck cancer: a cross-sectional 18F-FDG PET study

2026-05-08

Abstract excerpt

<h4>Background</h4> Head and neck cancer (HNC) uniquely threatens communication through its impact on voice and speech. The neural systems linking depressive symptoms with perceived voice handicap remain poorly characterized. We examined whether these symptom domains show dissociable associations with regional brain glucose metabolism. <h4>Methods</h4> We conducted a cross-sectional 18F FDG-PET study in 63 HNC...

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Literature Corpus work: 9292fc58-46d1-574c-bda8-f7e021579ff7
DOI: 10.64898/2026.05.07.26352637

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