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Alcohol-Related Risk, Depressive Symptoms, HRQoL, and Coping Phenotypes in Head-and-Neck Cancer: A Multicenter Cross-Sectional Study Stratified by Clinical Stage.

Medicina (Kaunas, Lithuania) - 1 Apr 2026

Hut Alexandru-Romulus, Iovanescu Gheorghe, Boia Eugen Radu, Horhat Delia Ioana, Dumitru Andrada Ioana, Galant Raphael, Rosca Cosmin, Kis Andreea Mihaela, Balica Nicolae Constantin

Abstract excerpt

Background and Objectives: Alcohol misuse, depressive symptoms, maladaptive coping, and impaired health-related quality of life (HRQoL) are clinically relevant in head-and-neck cancer, but their interrelationships are not fully captured by clinical stage alone. This multicenter study examined these domains at first admission and explored whether data-driven psychosocial phenotypes could complement stage-based...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42075543
DOI: 10.3390/medicina62040671
PMCID: PMC13117949

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COPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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