Article
microRNA-372 maintains oncogene characteristics by targeting TNFAIP1 and affects NFκB signaling in human gastric carcinoma cells.
International journal of oncology - 1 Feb 2013
Zhou Chang, Li Xiaofeng, Zhang Xiaoting, Liu Xizhi, Tan Zhiwen, Yang Celi, Zhang Jian
Abstract excerpt
Aberrant microRNA (miRNA) expression has been investigated in gastric cancer, which is one of the most common malignancies. However, the roles of miRNAs in gastric cancer remain largely unknown. In the present study, we found that microRNA-372 (miR-372) directly targets tumor necrosis factor, α-induced protein 1 (TNFAIP1), and is involved in the regulation of the NFκB signaling pathway. Furthermore,...
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