Article

<i>FOXK2</i> amplification and overexpression promotes breast cancer development and chemoresistance

2023-05-30

Abstract excerpt

Activation of oncogenes through DNA amplification/overexpression plays an important role in cancer initiation and progression. Chromosome 17 has many cancer-associated genetic anomalies. This cytogenetic anomaly is strongly associated with poor prognosis of breast cancer. FOXK2 gene is located on 17q25 and encodes a transcriptional factor with a forkhead DNA binding domain. By integrative analysis of public genom...

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Literature Corpus work: 920704af-a138-5e68-9be4-1b7772239c61
DOI: 10.1101/2023.05.28.542643

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