Article

Temporal phase-resolved transcriptomics reveals host determinants of Marek’s disease virus reactivation in transformed chicken T cells

2026-08-11

Abstract excerpt

<h4>ABSTRACT</h4> Marek’s disease virus (MDV) is an oncogenic herpesvirus that establishes latency in CD4⁺ T cells, from which it reactivates to initiate productive replication and dissemination. To define host mechanisms governing the transition from latency to early and late lytic replication, we developed recombinant MDV expressing early RLORF4mRFP and late UL47eGFP, which was used to isolate latent (Lo; mRFP...

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Literature Corpus work: 91fe7793-9237-5958-a112-66f433db7734
DOI: 10.64898/2026.08.10.743901

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