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Network controllability enrichment analysis reveals that SARS-CoV-2 infection tends to target indispensable nodes of a directed human protein-protein interaction network

2021-04-19

Abstract excerpt

<h4>ABSTRACT</h4> The COVID-19 disease has been a global threat caused by the new coronavirus species, SARS-CoV-2, since early 2020 with an urgent need for therapeutic interventions. In order to provide insight into human proteins targeted by SARS-CoV-2, here we study a directed human protein-protein interaction network (dhPPIN) based on our previous work on network controllability of virus targets. We previously...

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Literature Corpus work
91ead975-410f-58a9-99f1-5ed46f193684
DOI
10.1101/2021.04.18.440358
Open publication

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Network controllability enrichment analysis reveals that SARS-CoV-2 infection tends to target indispensable nodes of a directed human protein-protein interaction networkDOI 10.1101/2021.04.18.440358
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